Price: £395
Turnaround: 2 weeks
Appointment: 15 mins
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July 7, 2026
Facing an infertility diagnosis can be a complex and emotional journey. At City Walk In Clinic, we believe that knowledge is the first step toward a solution.
Our advanced Y Chromosome Deletion Testing provides crucial insights into the genetic causes of sperm production issues, empowering you and your specialist to make informed decisions about your path to parenthood.
The Y chromosome carries the genetic blueprint essential for male development and sperm production. Specific regions on this chromosome, known as the AZF regions (AZFa, AZFb, AZFc), contain the “master instructions” for creating sperm. A Y chromosome microdeletion occurs when small regions of the Y chromosome are missing.
This missing genetic material can disrupt sperm production, leading to various fertility challenges. The severity depends entirely on which region is affected:
For men with Y chromosome deletions, the impact on fertility can range from reduced sperm quality and motility to a low sperm count (oligospermia) or no sperm at all (azoospermia). This testing helps determine not only whether there is a genetic problem, but also how that problem will affect treatment.
Crucially, it helps doctors predict the likelihood of finding sperm directly in the testicles, which is a critical factor for procedures like ICSI (Intracytoplasmic Sperm Injection) during IVF.
It is important to understand that Y chromosome deletions are rarely inherited from the father.
In most cases, these are de novo (new) genetic changes. They typically occur spontaneously during the father’s sperm formation or in the early stages of embryo development.
While the exact trigger is often unknown, they can result from random errors during cell division. Because of this, having no family history of infertility does not rule out a genetic cause.
Y chromosome microdeletions are a significant cause of male infertility, affecting approximately 1 in 4,000 men and present in about 5% of UK men with severe sperm production issues. We typically recommend this test if you are:
Use our online booking engine or book your test by giving us a call.
On the online booking engine select the “appointment type” you need.
You will be seen by one of our friendly phlebotomists or trained clinicians.
We understand that medical tests can feel daunting. Our process is designed to be simple, discreet, and stress-free, ensuring you feel supported at every step.
No special preparation, like fasting, is required. However, we encourage you to be ready to discuss your medical and reproductive history with our doctor or nurse. Please inform us if you have a bleeding disorder or are taking blood-thinning medication, as the test involves a standard blood draw.
The procedure is quick and straightforward. An experienced doctor or nurse will draw a small blood sample from a vein in your arm, a process that typically takes less than 10 minutes. This sample is then securely sent to our specialised genetics laboratory for analysis using PCR (Polymerase Chain Reaction), which can accurately detect missing sections of the Y chromosome.
Your results will be available shortly, and a member of our clinical team will contact you personally to discuss them.
No
Hidden Charges
Transparent fees. The price you see is the price you pay.
No GP consultation
needed
No GP appointment requirement for blood tests
Established
since 1998
Experienced doctors & a professional team.
Strictly
confidential
Your medical records are kept private at all times.
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Trustindex verifies that the original source of the review is Yell. We offer a wide range of private blood tests in London. Same-day appointments are available 5 days a week.
We work with experienced consultants & healthcare professionals who have received positive feedback from our patients, and with whom we have established long-term relationships.
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