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Blood Tests > Coeliac Disease Test
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Coeliac disease is a chronic autoimmune disorder due to the digestion of gluten-a protein contained within wheat, barley, and rye. It affects about 1 in 100 people in the UK, though many cases remain undiagnosed.
It will result in serious complications if not diagnosed and treated. It includes malnutrition, osteoporosis, infertility, and predisposing to increased risks for certain types of cancers. The key is early detection; a Coeliac disease blood test is a sound first step toward diagnosing the condition.
If you experience persistent gastrointestinal symptoms such as bloating, diarrhoea, or abdominal pain, or if you suffer from fatigue, anaemia, or unexplained weight loss, this test may help identify Coeliac disease.
It is also recommended if you have a family history of the condition, as it can be hereditary.
Did you know that over 300 000 tests for Coeliac disease antibodies (e.g., tTG-IgA) are performed annually? While anyone can develop Coeliac disease, certain people are at a higher risk and should consider testing. You may be at an increased risk if:
The results of your Coeliac disease blood test will indicate whether your levels of these various antibodies are raised, which can help indicate the reaction of your immune system to gluten.
Left untreated, Coeliac disease can lead to significant health complications, including:
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Fasting is typically not required for a Coeliac disease blood test. You can eat normally unless otherwise advised by your healthcare provider. The test checks for antibodies that react to gluten, so avoiding gluten may result in false-negative results. Common gluten-containing foods include bread, pasta, and cereals. Prepare a list of any symptoms you are experiencing (e.g., bloating, diarrhoea, fatigue) and any family history of Coeliac disease. This information helps your healthcare provider better assess the results.
A healthcare professional will collect a small blood sample from a vein in your arm using a needle. The blood draw typically takes around 5 – 10 minutes. The entire appointment may last around 30 minutes, including paperwork and waiting time. If you are anxious about needles, inform us, so we can help make the experience as comfortable as possible. Feel free to ask your healthcare professional any questions about the procedure or discuss any symptoms you’re experiencing with your doctor.
Apply pressure to the puncture site to minimise bruising and keep the area clean. A small bandage will usually be applied. You may experience minor discomfort or bruising, but this should subside within a few days. The test results may take a few days to a week, depending on the lab. Your doctor will explain what the antibody levels indicate in relation to Coeliac disease. If the test shows elevated antibodies, further testing, such as a small intestine biopsy, may be recommended to confirm the diagnosis.
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